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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Pimozide Influence on protein activity Western Blot 2.50 µM KU812 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 5.00 µM KU812 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 7.50 µM KU812 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 10.00 µM KU812 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 10.00 µM K562 Homo sapiens p-STAT5
Pimozide Influence on protein activity Western Blot 10.00 µM K562 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 10.00 µM K562 Homo sapiens
Pimozide Influence on protein activity Western Blot 10.00 µM K562 Homo sapiens
Pimozide Influence on protein activity Western Blot 10.00 µM KU812 Homo sapiens
Pimozide Influence on protein activity Western Blot 10.00 µM KU812 Homo sapiens
Pimozide Influence on protein activity Western Blot 10.00 µM K562 Homo sapiens
Pimozide Influence on protein activity Western Blot 10.00 µM K562 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 1.00 µM KU812 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 2.50 µM KU812 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 5.00 µM KU812 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 7.50 µM KU812 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 10.00 µM KU812 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 1.00 µM K562 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 2.50 µM K562 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 5.00 µM K562 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 7.50 µM K562 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 10.00 µM K562 Homo sapiens
Pimozide Influence on cell viability Flow cytometry- Annexin 5.00 µM KU812 Homo sapiens
Pimozide Influence on protein activity in presence of imatinib Western Blot 5.00 µM KU812 Homo sapiens p-STAT5
Pimozide Influence on protein activity in presence of imatinib Western Blot 5.00 µM KU812 Homo sapiens STAT5
Pimozide Influence on cell viability in presence of imatinib ATP-dependent luminescence assay 5.00 µM KU812 Homo sapiens
Pimozide Influence on cell viability in presence of imatinib Flow cytometry- Annexin 5.00 µM KU812 Homo sapiens
Pimozide Influence on protein activity in presence of nilotinib Western Blot 5.00 µM K562 Homo sapiens
Pimozide Influence on protein activity in presence of nilotinib Western Blot 5.00 µM K562 Homo sapiens
Pimozide Influence on cell viability in presence of nilotinib ATP-dependent luminescence assay 5.00 µM K562 Homo sapiens
Pimozide Influence on gene expression RT-qPCR 5.00 µM unmutated BCR/ABL Homo sapiens
Pimozide Influence on gene expression RT-qPCR 5.00 µM unmutated BCR/ABL Homo sapiens
Pimozide Influence on gene expression RT-qPCR 5.00 µM unmutated BCR/ABL Homo sapiens
Pimozide Influence on gene expression RT-qPCR 5.00 µM unmutated BCR/ABL Homo sapiens
Pimozide Influence on protein activity Western Blot 5.00 µM Kit225 Homo sapiens p-STAT5
Pimozide Influence on protein activity Western Blot 7.50 µM Kit225 Homo sapiens p-STAT5
Pimozide Influence on protein activity Western Blot 10.00 µM Kit225 Homo sapiens p-STAT5
Pimozide Influence on protein activity Western Blot 15.00 µM Kit225 Homo sapiens p-STAT5
Pimozide Influence on protein activity Western Blot 20.00 µM Kit225 Homo sapiens p-STAT5
Pimozide Influence on protein activity Western Blot 5.00 µM Kit225 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 7.50 µM Kit225 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 10.00 µM Kit225 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 15.00 µM Kit225 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 20.00 µM Kit225 Homo sapiens STAT5
Pimozide Influence on protein activity Western Blot 5.00 µM Kit225 Homo sapiens
Pimozide Influence on protein activity Western Blot 7.50 µM Kit225 Homo sapiens
Pimozide Influence on protein activity Western Blot 10.00 µM Kit225 Homo sapiens
Pimozide Influence on protein activity Western Blot 15.00 µM Kit225 Homo sapiens
Pimozide Influence on protein activity Western Blot 20.00 µM Kit225 Homo sapiens
Pimozide Influence on protein activity Western Blot 5.00 µM HuT102 Homo sapiens p-STAT5